منابع مشابه
Toxic nephropathy: environmental chemicals.
The kidney is the target of numerous xenobiotic toxicants, including environmental chemicals. Anatomical, physiological, and biochemical features of the kidney make it particularly sensitive to many environmental compounds. Factors contributing to the sensitivity of the kidney include: large blood flow, the presence of a variety of xenobiotic transporters and metabolizing enzymes, and concentra...
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We describe an enzyme-linked immunosorbent assay (ELISA) for urinary albumin. It requires only commercially available reagents, can detect as little as 16 micrograms of albumin per liter, and analytical recovery ranges from 92 to 116%. The assay is simple, rapid, and inexpensive. Albumin excretion was 6.2 (SD 4.1) mg/24 h in healthy subjects (n = 40), 14.7 (SD 7.2) mg/24 h in albumin-test-strip...
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Since the introduction of our plasma cortisol enzyme-linked immunosorbent assay (ELISA) [l] using affinity purified antiserum [2] into the routine steroid laboratory, we have embarked on the development of a simple urinary free or unconjugated cortisol ELISA which would allow measurement of both urine and plasma cortisol on the one ELISA plate. This paper describes for the first time an ELISA f...
متن کاملUrinary biomarkers in obstructive nephropathy.
BACKGROUND AND OBJECTIVES Obstructive nephropathy is a leading cause of CKD in children. The assessment of severity of renal impairment and the prediction of which children will progress to renal failure are, however, challenging. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS This case-control study measured the urinary excretion of candidate biomarkers in 27 prevalent case-patients with post...
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Aspirin causes the desquamation of certain epithelial cells and this effect can be demonstrated both in the stomach and, in particular, in the kidney (Harvald, Valdorf-Hansen, and Nielsen, 1960; Harvald and Clausen, 1960; Scott, Denman, and Dorling, 1963; Prescott, 1965, 1966). In the case of the kidney the nephron is lined by a variety of different epithelial cells and it is not clear which of...
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ژورنال
عنوان ژورنال: Sangyo Igaku
سال: 1970
ISSN: 0047-1879,1881-1302
DOI: 10.1539/joh1959.12.6_299_1